Meaning of Intracranial Pressure-to-Blood Pressure Fisher-Transformed Pearson Correlation–Derived Optimal Cerebral Perfusion Pressure
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چکیده
منابع مشابه
Effect of etomidate on intracranial pressure and cerebral perfusion pressure.
Ten patients with intracranial lesions, anaesthetized with thiopentone and nitrous oxide (70%) in oxygen (30%) received etomidate 0.2 mg kg-1 i.v. Ventilation was controlled in each patient. Intracranial pressure (i.c.p.) and mean arterial pressure (m.a.p.) were recorded. I.c.p. decreased significantly in all patients (0.01 greater than P greater than 0.001). Although PaCO2 decreased during the...
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Intracranial pressure was raised by expansion of a supratentorial subdural ballon in anaesthetized baboons. Pressures were measured at several sites, both supratentorial and infratentorial, and cerebral blood flow was measured in each cerebral hemisphere separately. Pressures recorded from the right and left lateral ventricles corresponded closely throughout. Highly significant correlations wer...
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Update in Anaesthesia | www.worldanaesthesia.org CEREBRAl BlooD FloW The brain is unusual in that it is only able to withstand very short periods of lack of blood supply (ischaemia). This is because neurones produce energy (ATP) almost entirely by oxidative metabolism of substrates including glucose and ketone bodies, with very limited capacity for anaerobic metabolism. Without oxygen, energyde...
متن کاملEffect of cerebral perfusion pressure on cerebral cortical microvascular shunting at high intracranial pressure in rats.
BACKGROUND AND PURPOSE Recently, we showed that decreasing cerebral perfusion pressure (CPP) from 70 mm Hg to 50 mm Hg and 30 mm Hg by increasing intracranial pressure (ICP) with a fluid reservoir induces a transition from capillary (CAP) to microvascular shunt (MVS) flow in the uninjured rat brain. This transition was associated with tissue hypoxia, increased blood-brain barrier (BBB) permeabi...
متن کامل19 Management of Intracranial Pressure and Cerebral Perfusion
The treatment of traumatic brain injury is based on the conceptual distinction between primary and secondary injury. Primary injury comprises the immediate effects of impact. Secondary injury is due to factors other than the direct impact and may begin almost immediately or some time later. The distinction is of course, not so sharp. It is increasingly clear that the impact initiates a series o...
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ژورنال
عنوان ژورنال: Critical Care Medicine
سال: 2018
ISSN: 0090-3493
DOI: 10.1097/ccm.0000000000003434